cchfv hoti np peptides Search Results


cchfv hoti np peptides  (GenScript corporation)
90
GenScript corporation cchfv hoti np peptides
On D5 p.i., groups of mice ( N = 6) from Fig. were euthanized and evaluated for cellular immune responses to infection via ( a ) <t>IFNу</t> <t>ELISpot</t> shown as cumulative responses against peptides spanning the entire <t>CCHFV</t> NP (SFC: spot forming cells). For T-cell depletion study, WT C57BL6/J mice were ( b ) vaccinated with Sham or repNP RNA on day −28 relative to lethal CCHFV challenge. On days −5, −2, and +5 relative to CCHFV challenge, mice were treated with isotype or αCD4 and αCD8 antibody to deplete mice of T-cell populations. On D0, groups of mice were evaluated for immunological response to vaccine or treated with MAR1−5A3 antibody and infected with a lethal dose of 100 TCID 50 CCHFV strain UG3010. Mice ( N = 8) were ( c ) weighed daily and monitored for ( d ) survival until day 14 p.i., On D5 p.i., groups of mice ( N = 6) were evaluated for ( e ) depletion of CD4+ and CD8 + T-cell populations via Flow Cytometry. Antibody treatment achieved a 96.3% depletion of CD4 + T-cells and 98.5% depletion of CD8 + T-cells. In the second study, groups of WT C57BL6/J and CD8 −/− mice were vaccinated and infected as above. Mice ( N = 8) were ( f ) weighed daily and monitored for ( g ) survival until day 14 p.i. Dashed lines indicate limit of detection. Data shown as mean plus standard deviation. Significance was calculated using one-way ANOVA; ns P > 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. Exact p -values: ( d ) both P = 0.0002, ( g ) both P = 0.0002.
Cchfv Hoti Np Peptides, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cchfv hoti np peptides - by Bioz Stars, 2026-05
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cchfv strain hoti peptides  (GenScript corporation)
90
GenScript corporation cchfv strain hoti peptides
On D5 p.i., groups of mice ( N = 6) from Fig. were euthanized and evaluated for cellular immune responses to infection via ( a ) <t>IFNу</t> <t>ELISpot</t> shown as cumulative responses against peptides spanning the entire <t>CCHFV</t> NP (SFC: spot forming cells). For T-cell depletion study, WT C57BL6/J mice were ( b ) vaccinated with Sham or repNP RNA on day −28 relative to lethal CCHFV challenge. On days −5, −2, and +5 relative to CCHFV challenge, mice were treated with isotype or αCD4 and αCD8 antibody to deplete mice of T-cell populations. On D0, groups of mice were evaluated for immunological response to vaccine or treated with MAR1−5A3 antibody and infected with a lethal dose of 100 TCID 50 CCHFV strain UG3010. Mice ( N = 8) were ( c ) weighed daily and monitored for ( d ) survival until day 14 p.i., On D5 p.i., groups of mice ( N = 6) were evaluated for ( e ) depletion of CD4+ and CD8 + T-cell populations via Flow Cytometry. Antibody treatment achieved a 96.3% depletion of CD4 + T-cells and 98.5% depletion of CD8 + T-cells. In the second study, groups of WT C57BL6/J and CD8 −/− mice were vaccinated and infected as above. Mice ( N = 8) were ( f ) weighed daily and monitored for ( g ) survival until day 14 p.i. Dashed lines indicate limit of detection. Data shown as mean plus standard deviation. Significance was calculated using one-way ANOVA; ns P > 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. Exact p -values: ( d ) both P = 0.0002, ( g ) both P = 0.0002.
Cchfv Strain Hoti Peptides, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cchfv strain hoti peptides/product/GenScript corporation
Average 90 stars, based on 1 article reviews
cchfv strain hoti peptides - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
peptide library an overlapping peptide library comprising 60 peptides covering predicted epitopic sites on the np of cchfv was synthesized  (Mimotopes)
90
Mimotopes peptide library an overlapping peptide library comprising 60 peptides covering predicted epitopic sites on the np of cchfv was synthesized
On D5 p.i., groups of mice ( N = 6) from Fig. were euthanized and evaluated for cellular immune responses to infection via ( a ) <t>IFNу</t> <t>ELISpot</t> shown as cumulative responses against peptides spanning the entire <t>CCHFV</t> NP (SFC: spot forming cells). For T-cell depletion study, WT C57BL6/J mice were ( b ) vaccinated with Sham or repNP RNA on day −28 relative to lethal CCHFV challenge. On days −5, −2, and +5 relative to CCHFV challenge, mice were treated with isotype or αCD4 and αCD8 antibody to deplete mice of T-cell populations. On D0, groups of mice were evaluated for immunological response to vaccine or treated with MAR1−5A3 antibody and infected with a lethal dose of 100 TCID 50 CCHFV strain UG3010. Mice ( N = 8) were ( c ) weighed daily and monitored for ( d ) survival until day 14 p.i., On D5 p.i., groups of mice ( N = 6) were evaluated for ( e ) depletion of CD4+ and CD8 + T-cell populations via Flow Cytometry. Antibody treatment achieved a 96.3% depletion of CD4 + T-cells and 98.5% depletion of CD8 + T-cells. In the second study, groups of WT C57BL6/J and CD8 −/− mice were vaccinated and infected as above. Mice ( N = 8) were ( f ) weighed daily and monitored for ( g ) survival until day 14 p.i. Dashed lines indicate limit of detection. Data shown as mean plus standard deviation. Significance was calculated using one-way ANOVA; ns P > 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. Exact p -values: ( d ) both P = 0.0002, ( g ) both P = 0.0002.
Peptide Library An Overlapping Peptide Library Comprising 60 Peptides Covering Predicted Epitopic Sites On The Np Of Cchfv Was Synthesized, supplied by Mimotopes, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/peptide library an overlapping peptide library comprising 60 peptides covering predicted epitopic sites on the np of cchfv was synthesized/product/Mimotopes
Average 90 stars, based on 1 article reviews
peptide library an overlapping peptide library comprising 60 peptides covering predicted epitopic sites on the np of cchfv was synthesized - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier

Image Search Results


On D5 p.i., groups of mice ( N = 6) from Fig. were euthanized and evaluated for cellular immune responses to infection via ( a ) IFNу ELISpot shown as cumulative responses against peptides spanning the entire CCHFV NP (SFC: spot forming cells). For T-cell depletion study, WT C57BL6/J mice were ( b ) vaccinated with Sham or repNP RNA on day −28 relative to lethal CCHFV challenge. On days −5, −2, and +5 relative to CCHFV challenge, mice were treated with isotype or αCD4 and αCD8 antibody to deplete mice of T-cell populations. On D0, groups of mice were evaluated for immunological response to vaccine or treated with MAR1−5A3 antibody and infected with a lethal dose of 100 TCID 50 CCHFV strain UG3010. Mice ( N = 8) were ( c ) weighed daily and monitored for ( d ) survival until day 14 p.i., On D5 p.i., groups of mice ( N = 6) were evaluated for ( e ) depletion of CD4+ and CD8 + T-cell populations via Flow Cytometry. Antibody treatment achieved a 96.3% depletion of CD4 + T-cells and 98.5% depletion of CD8 + T-cells. In the second study, groups of WT C57BL6/J and CD8 −/− mice were vaccinated and infected as above. Mice ( N = 8) were ( f ) weighed daily and monitored for ( g ) survival until day 14 p.i. Dashed lines indicate limit of detection. Data shown as mean plus standard deviation. Significance was calculated using one-way ANOVA; ns P > 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. Exact p -values: ( d ) both P = 0.0002, ( g ) both P = 0.0002.

Journal: Nature Communications

Article Title: Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21

doi: 10.1038/s41467-024-53362-7

Figure Lengend Snippet: On D5 p.i., groups of mice ( N = 6) from Fig. were euthanized and evaluated for cellular immune responses to infection via ( a ) IFNу ELISpot shown as cumulative responses against peptides spanning the entire CCHFV NP (SFC: spot forming cells). For T-cell depletion study, WT C57BL6/J mice were ( b ) vaccinated with Sham or repNP RNA on day −28 relative to lethal CCHFV challenge. On days −5, −2, and +5 relative to CCHFV challenge, mice were treated with isotype or αCD4 and αCD8 antibody to deplete mice of T-cell populations. On D0, groups of mice were evaluated for immunological response to vaccine or treated with MAR1−5A3 antibody and infected with a lethal dose of 100 TCID 50 CCHFV strain UG3010. Mice ( N = 8) were ( c ) weighed daily and monitored for ( d ) survival until day 14 p.i., On D5 p.i., groups of mice ( N = 6) were evaluated for ( e ) depletion of CD4+ and CD8 + T-cell populations via Flow Cytometry. Antibody treatment achieved a 96.3% depletion of CD4 + T-cells and 98.5% depletion of CD8 + T-cells. In the second study, groups of WT C57BL6/J and CD8 −/− mice were vaccinated and infected as above. Mice ( N = 8) were ( f ) weighed daily and monitored for ( g ) survival until day 14 p.i. Dashed lines indicate limit of detection. Data shown as mean plus standard deviation. Significance was calculated using one-way ANOVA; ns P > 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. Exact p -values: ( d ) both P = 0.0002, ( g ) both P = 0.0002.

Article Snippet: To measure CCHFV-specific T-cell responses, an IFNγ ELISpot kit (ImmunoSpot) was used with peptides spanning the entire CCHFV Hoti NP (GenScript).

Techniques: Infection, Enzyme-linked Immunospot, Flow Cytometry, Standard Deviation